Analysis of Clinical Trials Using SAS

A Practical Guide


Authors: Alex Dmitrienko, Geert Molenberghs, Christy Chuang-Stein, Walter Offen

Publisher: SAS Press

For statisticians, essential information on applying statistical methods to clinical trials data.

Requires SAS/STAT.


Paperback (2005)


Year: 2005

ISBN: 1-59047-504-6

ISBN-13: 978-1-59047-504-1

Pages: 427

Publisher’s list price: 74.95


  • 1. Analysis of Stratified Data
  • 2. Multiple Comparisons and Multiple Endpoints
  • 3. Analysis of Safety and Diagnostic Data
  • 4. Interim Data Monitoring
  • 5. Analysis of Incomplete Data
  • Appendix
  • Index

From the Introduction

Clinical trials have long been one of the most important tools in the arsenal of clinicians and scientists who help develop pharmaceuticals, biologics, and medical devices. . . .

The aim of this book is unique in that we focus in great detail on a set of selected and practical problems facing statisticians and biomedical scientists conducting clinical research. We discuss solutions to these problems based on modern statistical methods and review computer-intensive techniques that help clinical researchers efficiently and rapidly implement these methods in the powerful SAS environment.

. . . Our choice of topics for this book was guided by the International Conference on Harmonization (ICH) guideline for the pharmaceutical industry entitled “Structure and Content of Clinical Study Reports” (this document is commonly referred to as ICH E3).